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  • Title: Undifferentiated carcinoma of the submandibular salivary gland with fulminant clinical course: a case report.
    Author: Rajendran R, Vidyarani, Nair PB, Dutt SC.
    Journal: Indian J Pathol Microbiol; 2006 Apr; 49(2):283-5. PubMed ID: 16933743.
    Abstract:
    Undifferentiated carcinoma of salivary glands is too poorly differentiated to be classified as any of the specific group of carcinomas. This is a rare disease, the incidence of which is rather low-to-very low in the Indian subcontinent. The tumor can assume an aggressive clinical behavior characterized by disseminated metastases. The prognosis is rated as dismal; as evidenced by this clinical report of a tumor in the submandibular salivary gland with synchronous metastases to the skull bones and in to the intracranial fossa. The putative relationship of the tumor to Epstein-Barr virus (EBV) infection is discussed.
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