These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Antiviral activity of substituted homoisoflavonoids on enteroviruses.
    Author: Tait S, Salvati AL, Desideri N, Fiore L.
    Journal: Antiviral Res; 2006 Dec; 72(3):252-5. PubMed ID: 16934879.
    Abstract:
    The antiviral activity of homoisoflavonoids, a class of flavonoids, was determined in vitro against a large panel of enteroviruses. The inhibition of viral replication was monitored on BGM (Buffalo Green Monkey) cells, and the concentration required for 50% inhibition (IC50), as well as the selectivity index (SI) were determined. None of the substances were effective against Sabin type 1 poliovirus (PV1), but most of them showed a low cytotoxicity and a marked antiviral activity against Coxsackie virus B1, B3, B4, A9 and echovirus 30.
    [Abstract] [Full Text] [Related] [New Search]