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  • Title: Synthesis of 2,4,6-trisubstituted pyrimidine and triazine heterocycles as antileishmanial agents.
    Author: Sunduru N, Agarwal A, Katiyar SB, Nishi, Goyal N, Gupta S, Chauhan PM.
    Journal: Bioorg Med Chem; 2006 Dec 01; 14(23):7706-15. PubMed ID: 16945542.
    Abstract:
    A series of 2,4,6 trisubstituted pyrimidines and triazines have been synthesized and screened for its in vitro antileishmanial activity profile in promastigote model. Nine compounds have shown > 94% inhibition against promastigotes at a concentration of 10 microg/mL.
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