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  • Title: Chapter 4: Burden and management of non-cancerous HPV-related conditions: HPV-6/11 disease.
    Author: Lacey CJ, Lowndes CM, Shah KV.
    Journal: Vaccine; 2006 Aug 31; 24 Suppl 3():S3/35-41. PubMed ID: 16950016.
    Abstract:
    Human Papillomavirus (HPV)-6 and -11 are the causative agents of ano-genital warts (GWs) and recurrent respiratory papillomatosis (RRP). They are low-risk HPV types that are uncommonly found in malignant lesions. GWs are an extremely prevalent sexually transmitted disease, whereas RRP is a rare disease that can be life threatening and requires multiple surgical procedures. GWs and RRP cause substantial healthcare costs. A quadrivalent HPV-6/11/16/18 vaccine (Merck/SPMSD) has shown essentially 100% protection against GWs in women in early studies. Cost-effectiveness analyses are needed to assess the benefits of the HPV-6/11 virus-like particle (VLP) components of the quadrivalent vaccine in population-based vaccination programmes.
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