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  • Title: Antimutagenic, antioxidant and antimicrobial properties of Maytenus krukovii bark.
    Author: Bruni R, Rossi D, Muzzoli M, Romagnoli C, Paganetto G, Besco E, Choquecillo F, Peralta K, Lora WS, Sacchetti G.
    Journal: Fitoterapia; 2006 Dec; 77(7-8):538-45. PubMed ID: 16963198.
    Abstract:
    The hydroalcoholic extract of Maytenus krukovii bark was investigated for its in vitro mutageno-protective activities by means of the Ames Salmonella/microsome assay. The extract showed an inhibitory effect in both T98 and T100 strains against the mutagenic activity of promutagen 2-aminoanthracene but was not protective against directly acting mutagens sodium azide and 2-nitrofluorene. When tested as a radical scavenger and antioxidant it produced a dose-dependent inhibition. The extract did not show significant antibacterial properties, and was weakly active against dermatophyte and phytopathogenic fungi, but inhibited the growth of phytopathogen Pithyum ultimum.
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