These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Specific inhibition of redox-linked proton pump activity of cytochrome oxidase by oleate hydroperoxide and involvement of ferrocytochrome c in the catabolism of hydroperoxide.
    Author: Yoshida S, Miki T, Orii Y, Takeshita M.
    Journal: Biochem Int; 1990; 21(1):33-40. PubMed ID: 1696818.
    Abstract:
    Both oleic acid and oleate hydroperoxide at concentrations below 200 nmol/mg asolectin remarkably depressed the proton pumping of cytochrome c oxidase reconstituted into liposomes but did not affect the respiratory control ratio. The inhibitory effect was comparable to that of N,N'-dicyclohexylcarbodiimide. Oleate hydroperoxide in the vesicles was reduced by ferrocytochrome c in the absence of cytochrome oxidase and converted to the hydroxy fatty acid. This non-enzymatic oxidation of ferrocytochrome c affected slightly the proton pumping and the cytochrome c oxidation by liposomal cytochrome oxidase. A physiological role of ferrocytochrome c in catabolism of the hydroperoxide of fatty acids is thus suggested.
    [Abstract] [Full Text] [Related] [New Search]