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  • Title: Pretreatment social functioning predicts 1-year outcome in early onset psychosis.
    Author: Meng H, Schimmelmann BG, Mohler B, Lambert M, Branik E, Koch E, Karle M, Strauss M, Preuss U, Amsler F, Riedesser P, Resch F, Bürgin D.
    Journal: Acta Psychiatr Scand; 2006 Oct; 114(4):249-56. PubMed ID: 16968362.
    Abstract:
    OBJECTIVE: The aim was to investigate the association of pretreatment social functioning (12 months before initial presentation) with symptom dimensions and social functioning at 1-year follow-up. METHOD: Fifty-six adolescents, age 14-18, first admitted for early onset psychosis, were evaluated at baseline and 1-year follow-up assessing psychopathology (PANSS), social functioning (Strauss and Carpenter Prognostic Scale), and duration of untreated psychosis (DUP). RESULTS: Adolescents with low pretreatment social functioning were at risk of more severe negative symptoms and lower social functioning at follow-up. Negative symptoms at baseline were less predictive and DUP was not predictive in this sample. CONCLUSION: Results of this study suggest a strong longitudinal inter-relatedness between social functioning and negative symptoms in this age group. An integrative treatment approach including family interventions, social skills training, long-term specialized work/school rehabilitation, and adequate antipsychotic treatment is warranted to improve both, social functioning and negative symptoms.
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