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  • Title: [Statistic correlation of carcinoembryonal antigen (CEA), alpha-feto protein (AFP) and isoenzymes of mitochondrial and BB creatine phosphokinase (CK+-BB and CK-MT) in patients with neoplasms].
    Author: Scarazatti E, Moscarella V, Garelli G, Melloni GF.
    Journal: Boll Soc Ital Biol Sper; 1990 Apr; 66(4):381-5. PubMed ID: 1697173.
    Abstract:
    In this work we have considered CK isoenzymes (CKBB-CKMT) as tumoral markers. The statistical comparison of the results (x2) executed on thirty neoplastic patients selected at random, has proved that CKBB and/or CKMT frequency is the same as the CEA one (CEA vs BB = N.S.; CEA VS MT = N.S.; CEA VS BB + MT = N.S.) and higher than AFP one (AFP VS BB = P less than 0.001; AFP VS MT = P less than 0.01). The isoenzymes' determination was executed by electrophoretic method (Helena) which is sensitive, specific and swift.
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