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Title: Calcium signaling: double duty for calcium at the mitochondrial uniporter. Author: Putney JW, Thomas AP. Journal: Curr Biol; 2006 Sep 19; 16(18):R812-5. PubMed ID: 16979553. Abstract: Uptake of Ca(2+) by mitochondria serves as a regulator of a number of important cellular functions, including energy metabolism, cytoplasmic Ca(2+) signals, and apoptosis. Recent findings reveal that the process of Ca(2+) uptake by the mitochondrial uniporter is itself regulated by Ca(2+) in a temporally complex manner.[Abstract] [Full Text] [Related] [New Search]