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  • Title: Microscopic polyangiitis associated with primary biliary cirrhosis: a causal or casual association?
    Author: Amezcua-Guerra LM, Prieto P, Bojalil R, Pineda C, Amigo MC.
    Journal: J Rheumatol; 2006 Nov; 33(11):2351-3. PubMed ID: 16981285.
    Abstract:
    The association between microscopic polyangiitis (MPA) and primary biliary cirrhosis (PBC) has seldom been reported. We describe a patient with PBC and MPA who presented with polyarthritis and pulmonary nodules followed by pauci-immune crescentic glomerulonephritis and liver dysfunction. Detection of p-ANCA, antimyeloperoxidase, and antimitochondrial antibodies along with liver and renal histopathology allowed a diagnosis of MPA and PBC. We also discuss 2 other cases that could be unrecognized associations of both diseases. Further reports are necessary to clarify if the coexistence between PBC and MPA is causal or casual.
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