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  • Title: Lidocaine-induced altered mental status and seizure after hematoma block.
    Author: Dorf E, Kuntz AF, Kelsey J, Holstege CP.
    Journal: J Emerg Med; 2006 Oct; 31(3):251-3. PubMed ID: 16982355.
    Abstract:
    Hematoma blocks with lidocaine are routinely utilized in the Emergency Department to allow reduction of Colles' fractures. Lidocaine toxicity is a potential complication of this procedure. We present a case report of a patient who developed acute mental status changes and generalized seizure immediately following administration of lidocaine during a hematoma block. The rapid onset of seizure development following injection was most likely due to inadvertent intravascular administration.
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