These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ascending afferents to the lateral cervical nucleus are enriched in glutamate-like immunoreactivity: a combined anterograde transport-immunogold study in the cat.
    Author: Broman J, Westman J, Ottersen OP.
    Journal: Brain Res; 1990 Jun 18; 520(1-2):178-91. PubMed ID: 1698503.
    Abstract:
    To investigate whether glutamate (Glu) may be a transmitter in terminals of ascending afferents to the lateral cervical nucleus (LCN), these terminals were identified by anterograde transport of wheatgerm agglutinin-horseradish peroxidase from the spinal cord, and their content of Glu-like immunoreactivity (Glu-LI) was assessed at the ultrastructural level by the immunogold technique. The gold particle density over the peroxidase-positive terminals of the spinocervical tract (SCT) was significantly higher (by a factor of 2.44) than over a reference terminal population containing flattened or pleomorphic vesicles. Further, LCN neurons were densely labeled by the Glu antiserum, although the gold particle density over neuronal cell bodies was not as high as in the SCT terminals. Previous investigations have shown enrichment of Glu-LI in putative glutamatergic terminals in other parts of the CNS. Hence, the present observations indicate that Glu may be a transmitter in the synapses between SCT terminals and LCN neurons. The cell body labeling in the LCN is more difficult to interpret because of possible interference of metabolic pools of glutamate.
    [Abstract] [Full Text] [Related] [New Search]