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  • Title: Has the United States population been adequately vaccinated to achieve rubella elimination?
    Author: Bloom S, Smith P, Stanwyck C, Stokley S.
    Journal: Clin Infect Dis; 2006 Nov 01; 43 Suppl 3():S141-5. PubMed ID: 16998773.
    Abstract:
    Mathematical models indicate that elimination of rubella virus transmission requires maintenance of approximately 90% rubella immunity among children. To evaluate whether rubella vaccination coverage among US preschool and school-age children is at levels consistent with rubella elimination, we reviewed data from 3 sources: (1) the Biologics Surveillance, which documents the net number of vaccine doses sold (1970-2004); (2) state immunization surveys of school entrants 5-6 years of age (1980-2005); and (3) the National Immunization Survey of children 19-35 months of age (1995-2004). Vaccine biologics data show that the net number of rubella vaccine doses sold was at least equivalent to the number of children born each year during 1970-2004. The average coverage for school-entrant surveys among reporting states was >95% for 1980-2004. National coverage among children 19-35 months of age was > or =90% overall for each year during 1995-2004. Three independent surveys suggest that childhood coverage with rubella-containing vaccine has been at sufficiently high levels to achieve elimination of rubella virus transmission.
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