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  • Title: Movement-related cortical activation in familial Parkinson disease.
    Author: Delval A, Defebvre L, Labyt E, Douay X, Bourriez JL, Waucquiez N, Derambure P, Destée A.
    Journal: Neurology; 2006 Sep 26; 67(6):1086-7. PubMed ID: 17000986.
    Abstract:
    We sought to determine whether or not first-degree relatives of patients with familial Parkinson disease (FDRs) present impaired movement-related cortical activity. We studied 10 familial Parkinson disease subjects, 10 FDRs, and 10 controls and analyzed event-related mu desynchronization (ERD) and beta synchronization. Forty percent FDRs presented reduced premovement mu ERD latency, suggesting that premovement cortical activation is impaired in FDRs.
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