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  • Title: [The dynamic indices of the natural killer cells in the chemotherapy of patients with digestive organ cancer].
    Author: Shparyk IaV.
    Journal: Vrach Delo; 1990 Jul; (7):14-6. PubMed ID: 1700552.
    Abstract:
    The author revealed a moderate inhibition of the large granule-containing lymphocytes and activity of natural killer cells during chemotherapy of 19 patients with cancer of the digestive organs. The suppression of functional indices was more pronounced in patients which underwent immediately before chemotherapy surgical treatment. Interferon and indomethacin restored in vitro the inhibited indices up to pretreatment values.
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