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  • Title: Native valve Aspergillus endocarditis in two patients with aplastic anaemia.
    Author: Petrikkos GL, Skiada A, Samonis G, Mavroudis D, Daikos GL.
    Journal: Scand J Infect Dis; 2006; 38(10):916-20. PubMed ID: 17008238.
    Abstract:
    Native valve fungal endocarditis is an uncommon disease with a high mortality rate. We present the clinical features, histological findings and outcome of 2 patients with native valve Aspergillus endocarditis. Both patients had aplastic anaemia as a predisposing disease. The diagnosis was made by Duke's criteria in 1 case and by histology in the other. Surgery was precluded owing to profound thrombocytopenia. Both patients had fatal outcome despite administration of liposomal amphotericin beta.
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