These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cyclophosphamide treatment of primary angiitis of the central nervous system in children: report of 2 cases.
    Author: Bitter KJ, Epstein LG, Melin-Aldana H, Curran JG, Miller ML.
    Journal: J Rheumatol; 2006 Oct; 33(10):2078-80. PubMed ID: 17014023.
    Abstract:
    Primary angiitis of the central nervous system (PACNS) is a rare, idiopathic vasculitis diagnosed most frequently in adults. We describe 2 children presenting with hemiplegia from PACNS treated with cyclophosphamide. Diagnosis in one child was based on abnormal angiography. Oral, but not intravenous (IV), cyclophosphamide was effective in preventing progressive weakness. The second child had unremarkable angiography, but brain biopsy revealed vasculitis; IV cyclophosphamide prevented further weakness. Both cases highlight the importance of early diagnosis and treatment.
    [Abstract] [Full Text] [Related] [New Search]