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  • Title: Plasma levels of basic fibroblast growth factor and vascular endothelial growth factor and their association with IgVH mutation status in patients with B-cell chronic lymphocytic leukemia.
    Author: Smolej L, Andrys C, Peková S, Schwarz J, Belada D, Zák P.
    Journal: Haematologica; 2006 Oct; 91(10):1432-3. PubMed ID: 17018398.
    Abstract:
    The mutation status of genes encoding the variable region of immunoglobulin heavy chains (IgV(H)) is a strong predictor of disease progression and survival in B-cell chronic lymphocytic leukemia (B-CLL). We investigated whether there is an association between the concentration of both vascular endothelial growth factor and basic fibroblast growth factor and IgV(H) mutation status in 49 untreated B-CLL patients.
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