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Title: A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma. Author: Chamberlain MC, Chalmers L. Journal: J Neurooncol; 2007 Apr; 82(2):207-9. PubMed ID: 17019532. Abstract: There is no standard of care for elderly patients (age>or=70 years) with newly diagnosed glioblastoma (GBM). In 15 consecutive patients (median age 79 years) treated with temozolomide (TMZ) (42 days on; 14 days off), median survival was 6 months (range 4-14 months). This pilot study suggests that low dose daily TMZ may represent an alternative and equally effective treatment to more traditionally administered radiotherapy.[Abstract] [Full Text] [Related] [New Search]