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Title: [Concentration of interleukine-8 in tears in patients with cystic fibrosis]. Author: Mrugacz M, Zelazowska B, Bakunowicz-Lazarczyk A, Minarowska A, Wysocka J. Journal: Klin Oczna; 2006; 108(4-6):184-5. PubMed ID: 17019991. Abstract: PURPOSE: To evaluate IL-8 concentration in tears fluid in cystic fibrosis patients. MATERIAL AND METHODS: Tears samples were collected from 18 CF Patients and 18 normal controls. Cytokine level was determined by ELISA. RESULTS: A significant increase of IL-8 concentration in tears fluid was found in CF patients compared with controls. CONCLUSIONS: Increase IL-8 concentration in tears fluid in CF patients suggests a role of immunologic processes in the pathogenesis of the ocular changes, and may be a marker of the inflammatory status in ocular surface in cystic fibrosis.[Abstract] [Full Text] [Related] [New Search]