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  • Title: Interferon-induced sarcoidosis.
    Author: Doyle MK, Berggren R, Magnus JH.
    Journal: J Clin Rheumatol; 2006 Oct; 12(5):241-8. PubMed ID: 17023810.
    Abstract:
    Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis. We present a case of a 59-year-old former intravenous drug user who developed systemic sarcoidosis while receiving interferon alpha and ribavirin for the treatment of chronic hepatitis C. Because interferons are increasingly prescribed by specialists in a variety of disciplines, rheumatologists should be aware of their potential to induce sarcoidosis as well as various autoimmune diseases.
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