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  • Title: On periodicity and directionality of somitogenesis.
    Author: Aulehla A, Pourquié O.
    Journal: Anat Embryol (Berl); 2006 Dec; 211 Suppl 1():3-8. PubMed ID: 17024300.
    Abstract:
    It is currently thought that the mechanism underlying somitogenesis is linked to a molecular oscillator, the segmentation clock, and to gradients of signaling molecules within the paraxial mesoderm. Here, we review the current picture of this segmentation clock and gradients, and use this knowledge to critically ask: What is the basis for periodicity and directionality of somitogenesis?
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