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  • Title: [Activity of human natural killer cells against target cells possessing different sensitivity to interferon].
    Author: Cheknev SB, Narovlianskiĭ AN, Amchenkova AM, Sorokin AM, Khesin IaE, Ershov FI.
    Journal: Biull Eksp Biol Med; 1990 Oct; 110(10):406-9. PubMed ID: 1703793.
    Abstract:
    The cytotoxic activity of peripheral blood natural killers (NK) against target cells (TC) J-96 and L-929 with high sensitivity to interferon (IFN) action, J-41 and MCB resistant to IFN action and line K-562 labelled by H3-uridine was studied in 14 hrs cytotoxic test. It has been shown that human TC J-96 didn't differ from the J-41 in their sensitivity to NK cytotoxicity and they are strongly resistant to NK than TC K-562. The murine TC L-929 as the human TC didn't differ from the MCB in their sensitivity to NK lysis and had also the same sensitivity to NK as the K-562 cells.
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