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  • Title: [Production of leukocyte-poor thrombocyte concentrates: results with a new kind of filter system].
    Author: Böck M, Salat C, Greither L, Heim MU, Weindler R, Bilas A, Mempel W.
    Journal: Beitr Infusionsther; 1990; 26():103-5. PubMed ID: 1703804.
    Abstract:
    A newly developed filter-system (Sepacell PL) for the removal of leukocytes from single donor platelet concentrates was tested. It removes contaminating leukocytes by 99.9%, the platelet loss was calculated as less than 1%. Platelet ultrastructure and function do not seem to be altered by the filtration. Therefore, the tested filter system seems to be a suitable device for leukocyte depletion of single donor platelet concentrates. Further clinical studies, however, are necessary to prove the efficiency of the filter system in preventing alloimmunization in vivo.
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