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  • Title: [Monoclonal antibodies to antigens of the Rh system].
    Author: Sonneborn HH, Ernst M.
    Journal: Beitr Infusionsther; 1990; 26():336-41. PubMed ID: 1703868.
    Abstract:
    For the development of monoclonal antibodies, which are useful for typing of Rh-system antigens, human monoclonal antibodies are needed. We have established a method for raising human monoclonal antibodies using EBV-transformation and subsequent stabilisation by fusing with mouse myeloma or heteromyeloma cell-lines. Using this method, we have produced several clones reacting with the D antigen which can be used for typing purposes as well as for research purposes to differentiate epitopes and categories.
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