These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Labial salivary gland biopsy in Sjögren's syndrome].
    Author: Dankof A, Morawietz L, Feist E.
    Journal: Pathologe; 2006 Nov; 27(6):416-21. PubMed ID: 17039338.
    Abstract:
    In the majority of cases, autoimmune sialadenitis is a feature of Sjögren's syndrome. This systemic autoimmune disease is, therefore, clinically characterised by sicca symptoms such as xerostomia and keratoconjunctivitis sicca. Since autoimmune sialadenitis affects major as well as minor salivary glands, histopathological examination is almost always carried out using labial salivary gland biopsies. A positive histopathological result is determined as a focal lymphocytic sialadenitis with at least one aggregate of 50 or more lymphocytes and histiocytes per 4 mm2 of salivary gland tissue. As one out of four objective findings, focus scoring belongs to the classification criteria for Sjögren's syndrome according to the American-European consensus group.
    [Abstract] [Full Text] [Related] [New Search]