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  • Title: [Harmine induces apoptosis in human SGC-7901 cells].
    Author: Song ZY, Liu JR, Lu XL, Wang LJ.
    Journal: Zhong Yao Cai; 2006 Jun; 29(6):571-3. PubMed ID: 17039880.
    Abstract:
    OBJECTIVE: [corrected] To investigate the effect of apoptosis induced in human SGC-7901 cells by Harmine. METHODS: The effect of Harmine on human SGC-7901 cell survival and apoptosis was determined by MTT assay, light microscopy and flow cytometry. Cell genomic DNA was detected by agarose electrophoresis. RESULTS: The survival of human SGC-7901 cells decreased; Apoptotic cells were observed by fluorescent microscope; FCM analysis showed that the peak of apoptosis increased. Typical DNA Ladder were detected in DNA agarose gel electrophoresis. CONCLUSION: HM can induce apoptosis in human SGC-7901 cells.
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