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  • Title: BHC induced testicular impairments in rats.
    Author: Chowdhury AR, Gautam AK.
    Journal: Indian J Physiol Pharmacol; 1990 Jul; 34(3):215-7. PubMed ID: 1704871.
    Abstract:
    Benzene hexachloride (BHC) was fed to mature male rats weighing 160 g at dosages of 3 and 6 mg/kg body weight over a period of 180 days. Significant decrease in testicular weight and degeneration of seminiferous tubules with deformed spermatogenic cells were noted at a dose of 6 mg/kg BHC. Marked increase in BHC residue in testis revealed that the drug was able to cross blood-testis barrier.
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