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  • Title: Homology and relationship between the genomes of papovaviruses, BK virus and simian virus 40.
    Author: Khoury G, Howley PM, Garon C, Mullarkey MF, Takemoto KK, Martin MA.
    Journal: Proc Natl Acad Sci U S A; 1975 Jul; 72(7):2563-7. PubMed ID: 170606.
    Abstract:
    A number of hybridization techniques have been used to assess the homology between the genomes of BK virus (BKV) and simian virus 40 (SV40). A noncontiguous set of homologous sequences has been localized primarily within the late region of the SV40 genome, and these sequences presumably account for the cross-reaction between V-antigens of the two viruses. The reason for the relatively strong crossreaction between SV40 and BKV T-antigens is still unclear. The sequence homology and similarity in genomic organization suggest a close relationship between these papovaviruses.
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