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  • Title: A comparison of calcofluor white, potassium hydroxide, and culture for the laboratory diagnosis of superficial fungal infection.
    Author: Haldane DJ, Robart E.
    Journal: Diagn Microbiol Infect Dis; 1990; 13(4):337-9. PubMed ID: 1706243.
    Abstract:
    A total of 207 skin scrapings were prospectively studied using potassium hydroxide (KOH), calcofluor white (CW), and culture to determine the clinical usefulness of each microscopic method. For dermatophytes (prevalence 13.2%), CW had a sensitivity of 92% and a specificity 95%, giving a positive predictive value of 74% and negative predictive value of 99%. KOH had a sensitivity of 88% and a specificity of 95%, giving a positive predictive value of 73% and a negative predictive value of 98%. CW was simple, rapid, and easy to read. For dermatophyte infection, CW results are as useful as KOH results.
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