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  • Title: Cytotoxic cycloartane triterpene saponins from Actaea asiatica.
    Author: Gao J, Huang F, Zhang J, Zhu G, Yang M, Xiao P.
    Journal: J Nat Prod; 2006 Oct; 69(10):1500-2. PubMed ID: 17067171.
    Abstract:
    Three new 9,19-cycloartane triterpene glycosides, asiaticoside A (1), asiaticoside B (2), and 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside (3), together with cimiacemoside I (4), 25-O-acetylcimigenol-3-beta-O-D-xyloside (5), and 25-anhydrocimigenol-beta-O-D-xyloside (6) were isolated from the roots/rhizomes extract of Actaea asiatica, and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR). Compounds 1-3, 5, and 6 had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
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