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  • Title: Failure of Listeria monocytogenes keratitis to respond to topical ofloxacin.
    Author: Altaie R, Fahy GT, Cormican M.
    Journal: Cornea; 2006 Aug; 25(7):849-50. PubMed ID: 17068464.
    Abstract:
    PURPOSE: The purpose of this case report is to demonstrate the need for identification of the offending pathogen in bacterial keratitis to guide appropriate treatment. METHODS: Case report. RESULTS: We report a case of Listeria monocytogenes keratitis in a young healthy adult that failed to respond to standard empirical therapy for bacterial keratitis but was treated successfully with topical ampicillin, chloramphenicol, and systemic amoxicillin. CONCLUSION: This case demonstrates the need for identification of the offending pathogen to guide appropriate treatment. It also demonstrates discrepancy between in vitro sensitivity and clinical response.
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