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  • Title: Recruitment of RNA polymerase to Class II CRP-dependent promoters is improved by a second upstream-bound CRP molecule.
    Author: Miroslavova NS, Mitchell JE, Tebbutt J, Busby SJ.
    Journal: Biochem Soc Trans; 2006 Dec; 34(Pt 6):1075-8. PubMed ID: 17073754.
    Abstract:
    Genetics and biochemistry have been exploited to investigate transcription activation by the Escherichia coli CRP (cAMP receptor protein) factor at promoters with a DNA site for CRP near position -41 and the effects of a second upstream-bound CRP molecule. We show that the upstream-bound CRP contributes to transcription activation by improving the recruitment of RNA polymerase.
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