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  • Title: [Pattern analytic investigations of blast cells in myelodysplastic syndrome and secondary acute myeloid leukemia].
    Author: Baumann I, Harms H, Kuse R, Feller AC, Müller-Hermelink HK.
    Journal: Verh Dtsch Ges Pathol; 1990; 74():135-8. PubMed ID: 1708571.
    Abstract:
    Blast-cells in Romanowsky-Giemsa stained bone marrow smears from 14 cases of primary myelodysplastic syndrome which consequently developed an acute myeloid leukemia and 28 cases of primary acute myeloid leukemia were analysed by a computer aided high resolution pattern recognition system. As control we used blast-cells from reactive affected bone marrow. Whereas blast-cell types in MDS and secondary AML showed overlapping features and a heterogenous distribution we could distinguish blasts in primary AML compared to "reactive" blasts. Opposite to this blasts in secondary AML showed no different pattern compared to "reactive" blast.
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