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  • Title: High amylase activity in pleural fluid and primary bronchogenic adenocarcinoma.
    Author: Devuyst O, Lambert M, Scheiff JM, Francart J.
    Journal: Eur Respir J; 1990 Nov; 3(10):1217-20. PubMed ID: 1708729.
    Abstract:
    We report a case of primary bronchogenic adenocarcinoma, complicated by pleural effusion, in which very high pleural amylase activity was found, whilst serum amylase was normal. Isoamylase determination showed a salivary-type amylase. Concerning the origin of this enzyme, ultrastructural study of the malignant cells obtained from the pleural fluid suggested a local amylase synthesis. The pathophysiological significance of electron-dense granules found in these cells is also discussed.
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