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  • Title: Clofazimine induced enteropathy--a case highlighting the importance of drug induced disease in differential diagnosis.
    Author: Mathew BS, Pulimood AB, Prasanna CG, Ramakrishna BS, Chandy SJ.
    Journal: Trop Gastroenterol; 2006; 27(2):87-8. PubMed ID: 17089619.
    Abstract:
    A patient on treatment for multibacillary leprosy for the past three years, presented with episodes of abdominal pain. Since the patient improved with conservative management, clofazimine induced enteropathy was considered as a remote possibility. A review of the mucosal biopsies showed macrophages with crystal-storing spaces consistent with clofazimine deposition in the duodenum. This case highlights the need to consider and investigate drug-induced disease as part of the differential diagnosis.
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