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  • Title: Lipases in beta-dipeptide synthesis in organic solvents.
    Author: Li XG, Kanerva LT.
    Journal: Org Lett; 2006 Nov 23; 8(24):5593-6. PubMed ID: 17107080.
    Abstract:
    A number of beta-dipeptides were prepared by two-step lipase-catalyzed reactions where N-acetylated beta-amino esters were first activated as 2,2,2-trifluoroethyl esters with Candida antarctica lipase B (CAL-B). The activated esters were then used to acylate beta-amino ester in the presence of Candida antarctica lipase A (CAL-A) in dry Et2O or i-Pr2O. [reaction: see text].
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