These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Stereochemically general approach to adjacent bis(tetrahydrofuran) cores of annonaceous acetogenins.
    Author: Wysocki LM, Dodge MW, Voight EA, Burke SD.
    Journal: Org Lett; 2006 Nov 23; 8(24):5637-40. PubMed ID: 17107091.
    Abstract:
    A series of six 2,5-disubstituted adjacent bis(tetrahydrofuran) stereoisomers with trans/erythro/cis, trans/threo/trans, or cis/threo/cis relative stereochemistry have been synthesized from known dihydroxycyclooctenes via ring opening/cross metathesis and Pd(0)-mediated asymmetric double cycloetherification. The stereochemistry of four of these isomers has been found in the biologically active annonaceous acetogenin natural products. [reaction: see text].
    [Abstract] [Full Text] [Related] [New Search]