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  • Title: [Beta-HCG positive seminoma--incidence with special reference to tumor marker concentration in testicular venous blood].
    Author: Mumperow E, Kressel K, Hartmann M.
    Journal: Urologe A; 1991 Mar; 30(2):114-6; discussion 117. PubMed ID: 1711727.
    Abstract:
    The treatment of so-called "marker-positive" pure seminoma is still a controversial subject. We report on 32 cases of seminoma treated within 2 years. In these we measured beta-HCG and AFP in a cubital vein and in the spermatic cord veins. While 78% of the patients affected had elevated beta-HCG levels in the spermatic cord, in only 25% elevated beta-HCG levels were found in a cubital vein. This shows the markedly higher sensitivity of marker evaluation in spermatic cord veins. Furthermore, we conclude that seminoma generally produces beta-HCG and that therefore no change of the usual principles of therapy is required.
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