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  • Title: Histological findings in cerebellar tonsils of patients with Chiari type I malformation.
    Author: Pueyrredon F, Spaho N, Arroyave I, Vinters H, Lazareff J.
    Journal: Childs Nerv Syst; 2007 Apr; 23(4):427-9. PubMed ID: 17119980.
    Abstract:
    OBJECTIVES: Cerebellar tonsillectomy is often performed for relief of symptoms associated with Chiari type I malformation (CMI). Nonetheless, the idea of removing supposedly healthy central nervous tissue has been a source of concern for neurosurgeons. The aim of this paper is to determine the histological changes in the cerebellar tonsils of patients with a wide range of symptoms and conditions related to CMI. MATERIALS AND METHODS: The cerebellar tonsils of 43 pediatric patients with CMI were sent to pathology for histological examination. CONCLUSION: The cerebellar tonsils in a great majority of CMI patients can be abnormal. We suggest that the reported histological findings are secondary to injury and ischemia.
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