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  • Title: Acute chorea associated with metoclopramide use.
    Author: Dubow JS, Leikin J, Rezak M.
    Journal: Am J Ther; 2006; 13(6):543-4. PubMed ID: 17122536.
    Abstract:
    Metoclopramide is a dopamine receptor antagonist that is used to treat diabetic gastroparesis, chemotherapy-induced nausea, and migraines. It is known to cause extrapyramidal side effects such as tardive dyskinesia, parkinsonism, dystonia, and akithisia, but not chorea. We describe a patient who presented with choreiform movements shortly after the administration of intravenous metoclopramide. Her work-up for secondary causes of chorea was otherwise negative and her symptoms abated with the administration of oral quetiapine and intravenous diazepam.
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