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  • Title: High-dose ziprasidone-induced acute dystonia.
    Author: Rosenfield PJ, Girgis RR, Gil R.
    Journal: Prog Neuropsychopharmacol Biol Psychiatry; 2007 Mar 30; 31(2):546-7. PubMed ID: 17123682.
    Abstract:
    There are few clinical data describing the relative risks of extrapyramidal symptoms (EPS) at higher doses of ziprasidone (i.e., greater than 160 mg/day) when compared to lower doses. We report on a patient who displayed no EPS with ziprasidone 160 mg/day for several months, but did display marked, acute dystonic reactions on ziprasidone 240 mg/day. The observations from the present case indicate that high-dose, ziprasidone-induced acute dystonia may occur even if no such side effects have been experienced at doses up to and including 160 mg/day.
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