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  • Title: Chemotherapeutic management of small bowel adenocarcinoma associated with Crohn's disease.
    Author: Bruckner HW, Hrehorovich VR, Sawhney HS, Meeus SI, Coopeman AM.
    Journal: J Chemother; 2006 Oct; 18(5):545-8. PubMed ID: 17127233.
    Abstract:
    Four patients with metastatic primary small bowel adenocarcinoma associated with Crohn's disease were successfully treated with low dose combination chemotherapy consisting of 5-fluorouracil, leucovorin and irinotecan with or without gemcitabine. Benefits included prolonged survival, objective responses, response of resistant tumors, downstaging, and a successful secondary complete resection (Ro) with a durable remission.
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