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  • Title: Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging.
    Author: Danesh-Meyer HV, Birch H, Ku JY, Carroll S, Gamble G.
    Journal: Neurology; 2006 Nov 28; 67(10):1852-4. PubMed ID: 17130422.
    Abstract:
    In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.
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