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  • Title: Are placental chorionic capillary nucleated red blood cell counts useful compared to umbilical cord blood tests?
    Author: McCarthy JM, Gilbert-Barness E, Tsibris JC, Spellacy WN.
    Journal: Fetal Diagn Ther; 2007; 22(2):121-3. PubMed ID: 17135757.
    Abstract:
    OBJECTIVE: To compare measurement of fetal nucleated red blood cell (NRBC) counts in paired histologic samples of the placenta and umbilical cord bloods. METHOD: Forty-five randomly selected pregnancies had two determinations of the NRBC count. A sample of umbilical venous blood had a NRBC count measured and sections of the placenta were examined for their villous capillary NRBC counts. RESULTS: Umbilical venous blood had NRBC/100 white blood cell counts ranging from 0 to 67. Paired evaluation of placental tissue had NRBC counts of 0-5 with 60% being zero compared to 8% zero counts in cord blood. There was no correlation between the paired counts (R(2) = 0.04). CONCLUSION: Umbilical cord blood provides different information on fetal NRBC count than does histologic study of the placenta.
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