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  • Title: Canine renal cortical necrosis and haemorrhage following ingestion of an Amitraz-formulated insecticide dip.
    Author: Oglesby PA, Joubert KE, Meiring T.
    Journal: J S Afr Vet Assoc; 2006 Sep; 77(3):160-3. PubMed ID: 17137059.
    Abstract:
    Amitraz is a formamidine compound used in veterinary medicine as a topical dip to control ticks and mites on dogs and livestock. A 10-year-old female Scottish terrier was presented following the accidental oral administration of a dip containing amitraz. This case report describes the clinical signs, treatment and pathology of this dog. Clinical signs of toxicity from amitraz result from stimulation of alpha2-adrenergic receptors. Amitraz is seldom fatal because the effects can be reversed by alpha2-adrenergic antagonists. The dog recovered from the amitraz toxicity but died 5 days later from acute renal failure.
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