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  • Title: Solid-state characterization of two polymorphic forms of R-albuterol sulfate.
    Author: Palacio MA, Cuffini S, Badini R, Karlsson A, Palacios SM.
    Journal: J Pharm Biomed Anal; 2007 Mar 12; 43(4):1531-4. PubMed ID: 17141446.
    Abstract:
    R-albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray powder diffraction, FT-IR spectroscopy, visual and microscopic inspection, and DSC. Substantial differences were observed between the solid-state properties of the crystals, confirming the existence of at least two polymorphic forms for R-albuterol sulfate: Form I and Form II.
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