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Title: To be or NUCB2, is nesfatin the answer? Author: Cowley MA, Grove KL. Journal: Cell Metab; 2006 Dec; 4(6):421-2. PubMed ID: 17141625. Abstract: Signals from the hypothalamus govern food intake and energy balance. A new study describes nesfatin-1, a hypothalamic and brainstem peptide whose expression decreases during fasting. Although central treatment with nesfatin-1 inhibited food intake and nesfatin-1 blockade increased food intake, the role and mechanism of nesfatin in energy balance remains unclear.[Abstract] [Full Text] [Related] [New Search]