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PUBMED FOR HANDHELDS

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  • Title: Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe.
    Author: Moran N, Bassani DM, Desvergne JP, Keiper S, Lowden PA, Vyle JS, Tucker JH.
    Journal: Chem Commun (Camb); 2006 Dec 28; (48):5003-5. PubMed ID: 17146508.
    Abstract:
    A novel anthracene-tagged oligonucleotide can discriminate between a fully-matched DNA target sequence and one with a single mismatching base-pair through a remarkable difference in fluorescence emission intensity upon duplex formation.
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