These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Crystallization and preliminary X-ray analysis of RNA oligomers containing CUG repeats which induce type 1 myotonic dystrophy.
    Author: Sato Y, Kimura K, Takénaka A.
    Journal: Nucleic Acids Symp Ser (Oxf); 2004; (48):117-8. PubMed ID: 17150506.
    Abstract:
    To reveal specific structure of CUG tandem repeats, which induce type 1 myotonic dystrophy, several fragments with different number of repeats have been synthesized, purified and crystallized. Their native PAGEs show that the structural stabilities of (CUG)6 and (CUG)7 are different, suggesting that when they adopt a hairpin form, the loops have different structures depending on the even and odd numbers of repeats. A preliminary structure of (CUG)6 crystal shows that the fragment forms a duplex similar to an A-form RNA.
    [Abstract] [Full Text] [Related] [New Search]